2021

 
 

4/19 (月)小川

Oide, M., et al., “Red light-induced structure changes in phytochrome A from Pisum sativum” Sci. Rep. 2021, 11, 2827.

https://www.nature.com/articles/s41598-021-82544-2


4/19 (月)小山田

Osman, D., et al., “Bacterial sensors define intracellular free energies for correct enzyme metalation.” Nat. Chem. Biol. 2019, 15, 241-249.

https://www.nature.com/articles/s41589-018-0211-4


4/26 (月)吉岡

Konarev, P. V., et al., “Ferredoxin competes with bacterial frataxin in binding to the desulfurase IscS” J. Biol. Chem. 2013, 288, 24777-24787.

https://www.sciencedirect.com/science/article/pii/S0021925820452299?via%3Dihub


4/26 (月)槇

Jagilinki, B. P., et al., “In vivo biogenesis of a de novo iron-sulfur cluster protein” ACS Synth. Biol. 2020, 9, 3400-3407.

https://pubs.acs.org/doi/10.1021/acssynbio.0c00514


5/10 (月)村上

Cranford-Smith, T., et al., “Iron is a ligand of SecA-like metal-binding domains in vivo” J. Biol. Chem. 2020, 295, 7516-7528.

https://www.sciencedirect.com/science/article/pii/S0021925817502811?via%3Dihub

5/10 (月)國近

Wensien, M., et al., “A lysine-cysteine redox switch with an NOS bridge regulates enzyme function”  in press.

https://www.nature.com/articles/s41586-021-03513-3

5/31 (月)小山田

Perkins, L., et al., “De novo biosynthesis of a nonnatural cobalt porphyrin cofactor in E. coli and incorporation into hemoproteins” Proc. Natl. Acad. Sci. USA 2021, 118, e2017625118.

https://www.pnas.org/content/118/16/e2017625118.abstract


5/31 (月) 槇

Fidai, I., et al., “Glutathione-complexed [2Fe-2S] clusters function in Fe-S cluster storage and trafficking”  J. Biol. Inorg. Chem. 2016, 21, 887-901.

https://pubmed.ncbi.nlm.nih.gov/27590019/


6/7 (月)吉岡

Eshelman, K., et al., “Inhibiting the BfrB:Bfd interaction in Psedomonas aeruginosa causes irreversible iron accumulation in bacterioferritin and iron defficiency in the bacterial cytosol” Metallomics 2017, 9, 646-659.

https://academic.oup.com/metallomics/article/9/6/646/6013721


6/7 (月) 村上

Stevens C.A. et al., “A minimalistic cyclic ice-binding peptide from phage display”  Nat. Commun. 2021, 12, 2675.

https://www.nature.com/articles/s41467-021-22883-w


6/14 (月)

Moore, S., et al., “Elucidation of the anaerobic pathway for the corrin component of cobalamin (vitamin B12)” Proc. Natl. Acad. Sci. USA 2013, 110, 14906-14911.

https://www.pnas.org/content/110/37/14906

6/14 (月) 高原

Sushuko, T. et al., “A new twist of rubredoxin function in M. tuberculosis”  Bioorg. Chem. 2021, 109, 104721.

https://www.sciencedirect.com/science/article/pii/S0045206821000973


ゼミ発表日時:2020年度 前期 毎週月曜9時30分

場所: zoomによるon-line開催.

過去の紹介論文はコチラ


研究報告会日時:2020年度 前期 月一回

日時・場所:zoomによるon-line開催.

9/27 (月) 大塚

Brewster J. L., et al., “Structures and kinetics of Thermotoga maritima MetY reveal new insights into the predominant sulfurylation enzyme of bacterial methionine biosynthesis” J. Biol. Chem. 2021, 296, 100797.

https://www.sciencedirect.com/science/article/pii/S0021925821005913?via%3Dihub


9/27 (月) 倉知

Anand K, et al., “Mycobacterium tuberculosis SufR responds to nitric oxide via its 4Fe-4S cluster and regulates Fe-S cluster biogenesis for persistence in mice” Redox Biol. 2021, 46, 102062.

https://www.sciencedirect.com/science/article/pii/S2213231721002214


10/4 (月) 高原

Ittarat W., et al., “Rubredoxin from the green sulfur bacterium Chlorobaculum tepidum do9nates a redox equivalent to the flavodiiron protein in an NAD(P)H dependent manner via ferredoxin-NAD(P)+ oxidoreductase” Arch. Microbiol. 2021, 203, 799-808.

https://link.springer.com/article/10.1007%2Fs00203-020-02079-4


10/4 (月)

Gashiri, G, et al., “A revised biosynthetic pathway for the cofactor F420 in prokaryotes” Nat. Commun. 2019, 10, 1558.

https://www.nature.com/articles/s41467-019-09534-x


10/11 (月) 吉岡

Phuong N. L VO, et al., “Optimized expression of Hfq protein increases Escherichia coli growth.” J. Biol. Enginner. 2021, 15, 7.

https://jbioleng.biomedcentral.com/articles/10.1186/s13036-021-00260-x


10/11 (月) 村上

Zhao, et al., “The Nbp35/ApbC homolog acts as a nonessential [4Fe-4S] transfer protein inmethanogenic archaea.” FEBS Lett. 2020, 594, 924-932.

https://febs.onlinelibrary.wiley.com/doi/full/10.1002/1873-3468.13673


10/11 (月)

Rosenbach, et al., “The Asp1 pyrophosphatase from S. pombe hosts a [2Fe-2S]2+ cluster in vivo. 2021, 26, 93-108.

https://link.springer.com/article/10.1007/s00775-020-01840-w



10/18 (月) 小山田

Inaba, et al., “Calix[3]pyrrole: A missing link in porphyrin-related chemistry” J. Am. Chem. Soc. 2021, 143, 12355-12360.

https://pubs.acs.org/doi/10.1021/jacs.1c06331


10/18 (月) 小川

Zhao, et al., “Design of an in-cell protein crystal for the environmentally responsible construction of a supramolecular filament.” Angew. Chem. Int. Ed. 2021, 60, 12341-12345.

https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202102039


10/25 (月) 市原

Zhang, et al. “Structural snapshots ofTRPV1 reveal mechanism of polymodal functionality” Cell 2021, 184, 5138-5150.

https://www.sciencedirect.com/science/article/pii/S009286742100982X?via%3Dihub


10/25(月) 高岡

Wittenborn, et al., “Structural insight into metallocofactor maturation in carbon monoxide dehydrogenase.” J. Biol. Chem. 2019, 294, 13017-13026.

https://www.sciencedirect.com/science/article/pii/S0021925820432375?via%3Dihub


11/1(月) 相羽

Maio, et al., “Fe-S cofadctors in the SARS-CoV-2 RNA-dependent RNA polymerase are potential antiviral targets.” Science 2021, 373, 236-241.

https://www.science.org/doi/10.1126/science.abi5224?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed


11/1(月) 國近

Esakova, et al., “Sructural basis for tRNA methylthiolation by the radical SAM enzyme MiaB.” Nature 2021, 597, 566-570.

https://www.nature.com/articles/s41586-021-03904-6


11/8 (月) 倉知

Liu, G., et al. “Heme biosynthesis depends on previously unrecognized acquisition of iron-sulfur cofactors in human amino-levulinic acid dehydratase” Nat. Commun.

https://www.nature.com/articles/s41467-020-20145-9


11/15(月) 大塚

Wang, H., et al., “Crystal structures clarifiy cofactor binding of plant tyrosine decarboxyase” Biochem. Biophys. Res. Commun. 2020, 523, 500-505.

https://www.sciencedirect.com/science/article/pii/S0006291X19324076


11/15(月) 高原

Scheurer, M., et al., “The rupture mechanism of rubredoxin is more complex than previously thought” Chem. Sci. 2020, 11, 6036.

https://pubs.rsc.org/en/content/articlelanding/2020/sc/d0sc02164d


11/15(月) 葛

Allen, K.D., et al., “Discovery of multiple modified F430 coenzymes in methanogens an anaerobic methanotrophic arcaea suggests possible new roles for F430 in nature” Appl. Environ. Microbiol. 2014, 80, 6403-6412.

https://journals.asm.org/doi/10.1128/AEM.02202-14


11/22(月) 高原

Williams, S.C., et al., “Investigation of the prevalence and catalytic activity of rubredoxin-fused alkane monoxygenases (AlkBs)” J. Inorg. Biochem. 2021, 219, 111409.

https://www.sciencedirect.com/science/article/pii/S0162013421000568


11/22(月) 吉岡

Vo, C.-D.-T., et al., “The O2-independent pathway of ubiquinone biosynthesis is essential for denitrification in Pseudomonas aeruginosa” J. Biol. Chem. 2020, 295, 9021-9032.


11/22(月) 小山田

Mayer, R. J., et al., “Mechanistic Insight into Metal Ion-Catalyzed Transamination” J. Am. Chem. Soc. 2021,143, 19099-19111.


12/6 槇

Hendricks, A. L., et al., “Characterization and Reconstitution of Human Lipoyl Synthase (LIAS) Supports ISCA2 and ISCU as Primary Cluster Donors and an Ordered Mechanism of Cluster Assembly” Int. J. Mol. Sci. 2021, 22, 1598.

https://www.mdpi.com/1422-0067/22/4/1598

12/6 村上

Reddy, S. S., et al., “Hydrogen bond surrogate-constrained dynamic antiparallel β-sheets” ChemBioChem 2021, 22, 2111-2115.

https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cbic.202100028

12/13 小川

Patwardan, et al., “Nickel–Sulfonate Mode of Substrate Binding for Forward and Reverse Reactions of Methyl-SCoM Reductase Suggest a Radical Mechanism Involving Long-Range Electron Transfer” J. Am. Chem. Soc. 2021, 143, 5481-5496.

https://pubs.acs.org/doi/10.1021/jacs.1c01086

12/13 市原

Jordan, et al., “Spontaneous assembly of redox-active iron-sulfur clusters at low concentrations of cysteine” Nat. Commun. 2021, 12, 5925.

https://www.nature.com/articles/s41467-021-26158-2

12/20 國近

Freibert, et al., “N-terminal tyrosine of ISCU2 triggers [2Fe-2S] cluster synthesis by ISCU2 dimerization” Nat. Commun. 2021, 12, 6902. https://www.nature.com/articles/s41467-021-27122-w

12/20 高岡

Hagen, et al., “EPR spectrscopy of putative enzyme intermediates in the NO reductase and the auto-nitrosylation reaction of Desulfovibrio vulgaris hybrid cluster protein” FEBS Lett., 2019, 593, 3075-3083.

https://febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.13539

12/20 相羽

Jain, et al., “Assembly of the [4Fe-4S] cluster of NFU1 requires the coordinated donation of two [2Fe-2S] clusters from the scaffold proteins, ISCU2 and ISCA1” Human Molecular genetics, 2020,  29, 3165-3182.

https://academic.oup.com/hmg/article/29/19/3165/5889935